Important Safety Information

Refer to the following important safety details for information on intended use, potential side effects and risks, considerations for specific groups, and possible drug interactions linked to the prescription treatments mentioned.

Amble encourages users to promptly report any side effects or adverse reactions to a licensed healthcare provider and the pharmacy that dispensed the medication. To report suspected reactions to acarbose, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

For emergencies, call 911 or go to your nearest emergency department.

Advertisements by Amble

All advertisements from joinamble.com are paid for by Amble Health, Inc. and are intended to market Amble’s services. Some advertisements may feature paid actors or dramatizations. When real Amble customers or endorsements are included, this will be clearly disclosed. Individual results may vary, and specific outcomes are not guaranteed.

Amble’s Role

Amble connects users with licensed healthcare providers for evaluations regarding the suitability of the treatments advertised. It may also assist with prescription coordination through an external pharmacy network.

Amble acts as a managed services provider and does not offer medical advice, fill prescriptions, or function as a licensed healthcare facility or pharmacy. Instead, it provides technology and administrative support to enable medical consultations and prescription logistics. For further details, see Amble’s Terms of Service.

Promotional Offers on joinamble.com

Occasionally, joinamble.com may present promotional pricing or special introductory offers. These promotions are valid for 24 hours after they are removed from the website.

The claim “same price at every dose” is subject to the following:

• Pricing may change at any time due to supply or market conditions at the discretion of joinamble.com.

• Any “same price at every dose” promotion expires within 24 hours of any price updates.

• Introductory or promotional pricing, including “first month” offers, are not governed by the “same price per dose” policy and only apply to full-price products as listed on the website.

Prescriptions and Medications

Prescription drugs require evaluation and approval by a qualified healthcare provider, and issuance is solely at the provider’s discretion. Access to treatment plans and medications is not assured.

Prescriptions issued through Amble may be filled by licensed pharmacies within its affiliated network.

All prescription medications involve potential risks. Please review all associated safety details and consult your provider for personalized advice.

Compounded Drug Formulations

In certain situations, healthcare providers may prescribe compounded medications, which are custom-prepared by certified compounding pharmacies based in the U.S. These medications are not FDA-approved for safety or effectiveness but may be used when alternatives are not available or appropriate.

Amble helps facilitate both FDA-approved and compounded medication fulfillment via its partner pharmacy network. These formulations are personalized to meet individual patient requirements and may differ from commercial products. FDA-approved substitutes may exist.

Trademark Notice

Ozempic® and Wegovy® are registered trademarks owned by Novo Nordisk A/S. Amble is not affiliated with or endorsed by the manufacturers of any brand-name medications. For further information, visit Novo Nordisk’s official website.

Contact Information

For any questions about Amble’s services or advertising content, please reach out to: hello@joinamble.com.

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Semaglutide

Important Safety Information Regarding Compounded Semaglutide Products

Please be aware that compounded drugs are not FDA-approved and do not undergo clinical studies to evaluate for safety and efficacy, similar to FDA-approved commercially available products. Compounded products may still be legally prescribed, and your healthcare provider may issue you a prescription for compounded semaglutide based on your medical consultation.

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of:

• 30 kg/m2 or greater (obesity) or
• 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

Speak with your healthcare provider to see if semaglutide may be right for you.

Semaglutide may cause serious side effects, including:

• Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, semaglutide caused thyroid tumors, including thyroid cancer. It is not known if semaglutide will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in humans.

Who should not use semaglutide:

• Do not use semaglutide if you or any family member has ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Do not use semaglutide if you have had a serious allergic reaction to semaglutide in the past.

Before starting semaglutide, tell your healthcare provider if you have any other medical conditions, including if you:

• Have or have had problems with your pancreas or kidneys.
• Have type 2 diabetes and a history of diabetic retinopathy.
• Have or have had depression, suicidal thoughts, or mental health issues.
• Are pregnant or plan to become pregnant. Semaglutide should not be used during pregnancy and there may be potential risks to an unborn baby from exposure to semaglutide during pregnancy. You should stop using semaglutide for at least 2 months before you plan to become pregnant.
• Are breastfeeding or plan to breastfeed. It is not known if semaglutide passes into your breast milk.

Tell your healthcare provider about all the medicines you take. This includes prescription medications, over-the-counter medicines, vitamins, and herbal supplements. Semaglutide may affect the way some medicines work, and some medicines may affect the way semaglutide works.

Serious side effects can occur with semaglutide. You or a caregiver should carefully monitor for these side effects, especially in the beginning of treatment and with dosage changes. Semaglutide may cause serious side effects, including:

• Thyroid C-Cell Tumors. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, semaglutide caused thyroid tumors, including thyroid cancer. It is not known if semaglutide will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in humans.
• Paralysis of the stomach (gastroparesis). The symptoms of gastroparesis may include feeling full shortly after starting a meal, feeling full long after eating a meal, nausea, and vomiting. Contact your healthcare provider if you experience any of these symptoms.
• Inflammation of your pancreas (pancreatitis). Stop using semaglutide and contact your healthcare provider immediately if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting.
• Gallbladder problems. Semaglutide may cause gallbladder problems, including gallstones. Some gallstones may need surgery. Contact your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools.
• Increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes. Signs and symptoms of low blood sugar may include dizziness or light-headedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, or feeling jittery. Talk to your healthcare provider about how to recognize and treat low blood sugar and check your blood sugar before you start and while you take semaglutide.
• Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration.
• Serious allergic reactions. Stop using semaglutide and seek medical attention if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
• Change in vision in people with type 2 diabetes. Tell your healthcare provider if you have changes in vision with semaglutide.
• Increased heart rate. Semaglutide may increase your heart rate while you are at rest. Talk to your healthcare provider if you feel your heart racing or pounding.
• Depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings. Contact your healthcare provider immediately if you have any mental changes that are new, worse, or worry you.

The most common side effects of semaglutide may include: nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, gas, stomach flu, heartburn, and runny nose or sore throat.

If you are experiencing a medical emergency, call 911 or seek immediate medical attention.

You are encouraged to report negative side effects of prescription products:

• Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch

Semaglutide administration. Semaglutide can be taken with or without food. The medication is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day every week. For detailed instructions on how to administer your dose, please speak with your healthcare provider. They will guide you on a treatment regimen and explain to self-administer the medication. You should not change your dosing regimen or stop taking semaglutide as prescribed without first discussing with your healthcare provider.

This information is not comprehensive. Please discuss with your healthcare provider any questions or concerns you have regarding semaglutide.

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Tirzepatide

Important Safety Information Regarding Compounded Tirzepatide Products

Please be aware that compounded drugs are not FDA-approved and do not undergo clinical studies to evaluate for safety and efficacy, similar to FDA-approved commercially available products. Compounded products may still be legally prescribed, and your healthcare provider may issue you a prescription for compounded tirzepatide based on your medical consultation.

Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of:

• 30 kg/m2 or greater (obesity) or
• 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia, obstructive sleep apnea or cardiovascular disease).

Speak with your healthcare provider to see if tirzepatide may be right for you.

Tirzepatide may cause serious side effects, including:

• Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, tirzepatide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors. It is unknown whether tirzepatide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans.

Who should not use tirzepatide:

• Do not use tirzepatide if you or any family member has ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Do not use tirzepatide if you have had a serious allergic reaction to tirzepatide in the past.

Before starting tirzepatide, tell your healthcare provider if you have any other medical conditions, including if you:

• Have or have had problems with your pancreas or kidneys.
• Have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food.
• Have a history of diabetic retinopathy.
• Have or have had depression, suicidal thoughts, or mental health issues.
• Are pregnant or plan to become pregnant. Tirzepatide should not be used during pregnancy and there may be potential risks to an unborn baby from exposure to tirzepatide during pregnancy. You should discuss with your healthcare provider whether and how you should stop using tirzepatide before you plan to become pregnant.
• Are breastfeeding or plan to breastfeed. It is not known if tirzepatide passes into your breast milk.

Tell your healthcare provider about all the medicines you take. This includes prescription medications, over-the-counter medicines, vitamins, and herbal supplements. Tirzepatide may affect the way some medicines work, and some medicines may affect the way tirzepatide works. If you are taking medicines to treat diabetes, including insulin or sulfonylureas, please let your healthcare provider know as tirzepatide could increase your risk of low blood sugar.

Serious side effects can occur with tirzepatide**. You or a caregiver should carefully monitor for these side effects, especially in the beginning of treatment and with dosage changes. Tirzepatide** may cause serious side effects, including:

• Thyroid C-Cell Tumors. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, tirzepatide caused thyroid tumors, including thyroid cancer. It is not known if tirzepatide will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in humans.
• Paralysis of the stomach (gastroparesis). The symptoms of gastroparesis may include feeling full shortly after starting a meal, feeling full long after eating a meal, nausea, and vomiting. Contact your healthcare provider if you experience any of these symptoms. Tirzepatide has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis, and is therefore not recommended in these patients.
• Inflammation of your pancreas (pancreatitis). Stop using tirzepatide and contact your healthcare provider immediately if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting.
• Gallbladder problems. Tirzepatide may cause gallbladder problems, including gallstones. Some gallstones may need surgery. Contact your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools.
• Increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes. Signs and symptoms of low blood sugar may include dizziness or light-headedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, or feeling jittery. Talk to your healthcare provider about how to recognize and treat low blood sugar and check your blood sugar before you start and while you take tirzepatide.
• Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration.
• Serious allergic reactions. Stop using tirzepatide and seek medical attention if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
• Change in vision in people with type 2 diabetes. Tell your healthcare provider if you have changes in vision with tirzepatide.
• Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use tirzepatide with medicines that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness or feeling jittery.
• Depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings. Contact your healthcare provider immediately if you have any mental changes that are new, worse, or worry you.

The most common side effects of tirzepatide include: nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, indigestion, injection site reactions, feeling tired, allergic reactions, belching, hair loss, and heartburn. These are not all the possible side effects of tirzepatide. Talk to your healthcare provider about any side effect that bothers you or doesn’t go away.

If you are experiencing a medical emergency, call 911 or seek immediate medical attention.

You are encouraged to report negative side effects of prescription products:

• Contact FDA MedWatch at 1-800-FDA-1088 or visit www.fda.gov/medwatch

Tirzepatide administration. The medication is self-administered as a subcutaneous injection in the stomach, thigh, or upper arm once a week on the same day every week. For detailed instructions on how to administer your dose, please speak with your healthcare provider. They will guide you on a treatment regimen and explain to self-administer the medication. You should not change your dosing regimen or stop taking tirzepatide as prescribed without first discussing with your healthcare provider.

This information is not comprehensive. Please discuss with your healthcare provider any questions or concerns you have regarding tirzepatide.

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Sermorelin

Safety Profile

Most side effects are mild and tend to resolve without intervention.

Common Side Effects

• Discomfort, redness, or swelling at the injection site

Less Common Side Effects

• Itching

• Difficulty swallowing

• Lightheadedness

• Flushed skin

• Headache

• Fatigue

• Restlessness

Avoid Sermorelin If You:

• Are allergic to Sermorelin or any of its ingredients

• Are pregnant or nursing

• Have active cancer

Precautions

Routine monitoring of growth hormone levels, blood glucose, and overall health is advised during use.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any condition.

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NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of the body, playing a key role in energy production, cellular repair, and overall metabolic function. At Amble, we make access to compounded NAD+ injections simple and safe—connecting you with licensed providers and trusted state-licensed pharmacies.

Please note: The NAD+ offered through Amble is not FDA-approved. It is compounded and dispensed by licensed pharmacies following a personalized telehealth consultation with a certified medical provider.

‍Warnings & Precautions

Your safety matters to us. Before starting NAD+ therapy, here are a few important considerations:

• Avoid use during pregnancy or breastfeeding. Please consult with your provider.
• Use with caution if you’ve experienced allergic reactions to NAD+ or any components in the injection.
• Let your provider know if you have any autoimmune, metabolic, or chronic conditions—or if you're taking any medications that could affect NAD+ metabolism.
• This product is not intended to diagnose, treat, cure, or prevent any disease.
• Only follow the dosing schedule recommended by your licensed provider. Injections are meant to be administered subcutaneously.
• Maximum dose: 0.5mL per injection.

‍Possible Side Effects

Most people tolerate NAD+ injections well, but some may experience:

• Mild redness, tenderness, or soreness at the injection site
• Warmth or flushing
• Lightheadedness, nausea, or brief fatigue
• In rare cases, allergic reactions—seek immediate care if you experience severe symptoms

Tips to reduce discomfort:

• Inject slowly over 20–30 seconds
• Rotate injection sites to avoid irritation

‍Drug Interactions

No major interactions have been reported. However, it’s essential to share your full supplement and medication list with your Amble provider during your consultation.

‍A Few Final Notes

• This compounded NAD+ formulation is not approved by the FDA.
• Amble is not a pharmacy and does not manufacture medications. Instead, we thoughtfully connect you with experienced healthcare professionals who evaluate your needs and coordinate treatment through reputable, licensed pharmacies.

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